Maria Jakobäa of Baden-Sponheim (25 June 1507 – 16 November 1580) was a German noblewoman and duchess consort of Bavaria.
Maria was the daughter of Philip I, Margrave of Baden and Countess Elisabeth, daughter of Philip, Elector Palatine and princess Margarete von Bayern-Landshut. Her paternal grandparents were Christopher I, Margrave of Baden-Baden and Ottilie of Katzenelnbogen.
On 5 October 1522 she married William IV, Duke of Bavaria, eldest son of Albert IV and his wife Kunigunde of Austria. They had four children:
Albert V (1528–1579) ∞ 1546 Archduchess Anna of Austria (1528–1590)
Mechthild of Bavaria (1532–1565) ∞ 1557 Margrave Philibert of Baden-Baden (1536–1569)
Hans and Marga Rall: Die Wittelsbacher – Von Otto I. bis Elisabeth I., Weltbild (1994) ISBN 3-85001-485-1